Isu tinoshandisa makuki kuwedzera ruzivo rwako.Nekuramba uchitsvaga webhusaiti ino, unobvuma kushandisa kwedu makuki.Mamwe mashoko.
Pane kudiwa kwekukurumidzira kweiyo biomedical yekutsvagisa mishumo yemasero anoyamwisa kuti ave akaenzana uye ane hudzamu, uye kutonga zvirinani uye kuyera mamiriro ezvakatipoteredza etsika tsika.Izvi zvichaita kuti kuenzanisa kwefiziology yemunhu kuve kwakaringana uye kunobatsira mukuberekana kwetsvagiridzo.
Chikwata chemasaenzi eKAUST nevamwe vaanoshanda navo muSaudi Arabia neUnited States vakaongorora mapepa mazana masere negumi akasarudzwa zvisina tsarukano pamitsara yemasero emammalian.Vasingasviki mazana manomwe avo vaisanganisira 1,749 ega ega masero tsika kuyedza, kusanganisira yakakodzera data pamusoro pemamiriro ekunze kwesero tsika yepakati.Ongororo yechikwata ichi inoratidza kuti rakawanda basa rinofanirwa kuitwa kugadzirisa kukosha uye kuberekana kwezvidzidzo zvakadaro.
Ridza masero mune inodzorwa incubator zvinoenderana neyakajairwa maprotocol.Asi masero achakura uye "kufema" nekufamba kwenguva, kuchinjana gasi nemhoteredzo yakapoteredza.Izvi zvinokanganisa nharaunda yenzvimbo mavanokura, uye zvinogona kushandura acidity yetsika, okisijeni yakanyungudika, uye carbon dioxide parameters.Shanduko idzi dzinokanganisa kushanda kwesero uye dzinogona kuita kuti chimiro chemuviri chisiyane nemamiriro ari mumuviri wemunhu mupenyu.
"Ongororo yedu inosimbisa mwero uyo masayendisiti anoregeredza kutarisa uye kudzora nharaunda yemasero, uye kusvika pamwero wekuti mishumo inovagonesa kusvika kumhedzisiro yesainzi nenzira dzakananga," akadaro Klein.
Semuenzaniso, vaongorori vakawana kuti inenge hafu yemapepa ekuongorora yakatadza kuzivisa tembiricha uye carbon dioxide marongero emasero etsika dzavo.Vasingasviki 10% vakashuma zviri mumhepo yeokisijeni muincubator, uye isingasviki 0.01% yakashuma acidity yepakati.Hapana mapepa akashumwa pamusoro peokisijeni yakanyungudika kana kabhoni dhayokisaidhi munhau.
Isu tinoshamiswa zvikuru kuti vatsvakurudzi vakanyanya kufuratira izvo zvakatipoteredza izvo zvinochengetedza physiologically mazinga akakodzera panguva yose yemaitiro emasero, zvakadai setsika acidity, kunyange zvazvo zvichinyatsozivikanwa kuti izvi zvakakosha pakushanda kwesero.”
Chikwata ichi chinotungamirwa naCarlos Duarte, nyanzvi yezvipenyu zvemugungwa kuKAUST, naMo Li, stem cell biologist, vachibatsirana naJuan Carlos Izpisua Belmonte, anovandudza biologist kuSalk Institute.Parizvino ari purofesa anoshanyira kuKAUST uye anokurudzira kuti biomedical masayendisiti kugadzira mishumo yakajairwa Uye kutonga uye kuyerwa maitiro, kunze kwekushandisa zvakakosha zviridzwa kudzora nharaunda yetsika yemhando dzakasiyana siyana.Majenari eSainzi anofanirwa kumisa miitiro yekubika uye inoda kutariswa kwakakwana uye kutonga kwe acidity yemedia, mweya wakanyungudika uye carbon dioxide.
"Zvirinani kushuma, kuyera, uye kutonga mamiriro ezvakatipoteredza etsika tsika kunofanirwa kuvandudza kugona kwesainzi kudzokorora uye kuburitsa mhedzisiro yekuedza," anodaro Alsolami."Kunyatsotarisisa kunogona kufambisa zvitsva uye kuwedzera kukosha kwe preclinical research kumuviri wemunhu."
"Mammalian cell tsika ndiyo hwaro hwekugadzirwa kwejekiseni rehutachiona uye humwe hunyanzvi hwekugadzira zvinhu," anotsanangura kudaro musayendisiti wezvemugungwa Shannon Klein."Asati aongororwa pamhuka nevanhu, anoshandiswa kudzidza basic cell biology, kudzokorora nzira dzechirwere, uye kudzidza huturu hwemishonga mitsva."
Klein, SG, etc. (2021) Kuregeredzwa kwakawanda kwekudzora kwezvakatipoteredza mutsika dzemammalian cell kunoda maitiro akanaka.Natural Biomedical Engineering.doi.org/10.1038/s41551-021-00775-0.
Tags: B sero, sero, sero tsika, incubator, mammalian cell, kugadzira, okisijeni, pH, physiology, preclinical, tsvagiridzo, T sero
Mubvunzurudzo iyi, Muzvinafundo John Rossen akataura nezve chizvarwa chinotevera kutevedzana uye kukanganisa kwayo pakuongororwa kwechirwere.
Mubvunzurudzo iyi, News-Medical yakataura naProfessor Dana Crawford nezvebasa rake rekutsvagisa panguva yeCOVID-19 denda.
Mubvunzurudzo iyi, News-Medical yakataura naDr. Neeraj Narula pamusoro pezvekudya zvakagadziriswa uye kuti izvi zvinogona sei kuwedzera njodzi yako yekuzvimba bowel chirwere (IBD).
News-Medical.Net inopa iyi ruzivo rwezvekurapa sevhisi zvinoenderana nemirairo nemamiriro aya.Ndokumbira utarise kuti ruzivo rwezvekurapa pawebhusaiti ino rwakaitirwa kutsigira pane kutsiva hukama pakati pevarwere nanachiremba/vanachiremba uye zano rekurapa ravanogona kupa.
Nguva yekutumira: Sep-07-2021
